Wemindji is accessible by car on a 95km gravel road that was built in 1995 that connects to the James Bay highway at km518. The James Bay highway begins south at Matagami and ends north at Radisson with a total of 620 km. The James Bay Highway gives coastal Cree communities access to urban areas in the south.
The community is also accessible by Air Creebec a Cree Owned air flight provider of the James Bay Region. Flights can be accessed from Montreal Trudeau Airport, Chibougamou, Valdor, and Timmons airport. The distance between Montreal from Wemindji is approximately 1, 400 km that takes approximately 18 hours of driving and a 5-hour flight